Principal Bioinformatics Software Engineer

apartmentRoche placeMississauga calendar_month 
Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs.

Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come.

Creating a world where we all have more time with the people we love.

That’s what makes us Roche.

Roche Diagnostics is a cutting-edge biotechnology company dedicated to advancing the field of genomics and diagnostics. We are at the forefront of developing state-of-the-art Next Generation Sequencing (NGS) technologies for diagnostic products and internal research and development.

Our team is composed of forward-thinking scientists, engineers, and researchers who are passionate about revolutionizing healthcare through innovation. We are seeking a highly motivated and experienced Software Engineer to join our growing team and contribute to the development of high-performance, high-quality NGS bioinformatics algorithms.

As a Principal Software Engineer specializing in Next Generation Sequencing Bioinformatics at Roche Diagnostics, you will play a critical role in designing, developing, and optimizing cutting-edge algorithms to extract meaningful insights from genomic data.

This position offers a unique opportunity to work on innovative projects that impact the fields of diagnostics and precision medicine. You will work closely with cross-functional teams of biologists, data scientists, and software engineers to build robust, scalable, and efficient software solutions.

Your Opportunity
  • Design, develop, and implement high-performance bioinformatics algorithms for analyzing NGS data, including variant calling, quality control, and data preprocessing.
  • Continuously optimize and refactor existing algorithms to improve performance and reduce resource utilization, enabling efficient analysis of large-scale genomic datasets.
  • Ensure the reliability and accuracy of bioinformatics algorithms by writing rigorous test suites and collaborating with quality assurance teams to validate results.
  • Integrate bioinformatics algorithms into the company's software platforms, ensuring seamless compatibility with existing pipelines and workflows.
  • Collaborate with biologists, data scientists, and other software engineers to understand the specific requirements and constraints of NGS data analysis for diagnostics and internal research.
  • Create detailed documentation for algorithms, code, and workflows to facilitate knowledge transfer and ensure reproducibility.
  • Mentor and provide technical guidance to junior engineers, fostering a culture of innovation and learning within the team.
Who you are
  • Bachelor's or higher degree in Computer Science, Bioinformatics, Computational Biology, or a related field with 5 plus years' of experience in relevant bioinformatics tools and libraries.
  • Strong proficiency in C++, with knowledge of scientific computing programming languages like Python and R
  • Experience with parallel computing, optimization, and performance tuning.
  • Experience with deeply understanding and optimizing complex algorithms.
  • Excellent problem-solving skills, attention to detail, and effective communication and teamwork abilities.
Preferred
  • Experience working in a regulated environment (e.g., ISO 13485, CLIA) is a plus.
  • Proven experience in developing bioinformatics algorithms for NGS data analysis.

Relocation benefits are not available for this posting

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Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche Pharma Canada has its office in Mississauga, Ontario and employs over 850 employees. The Mississauga facility is bright, vibrant, fosters collaboration and teamwork, and is reflective of Roche's truly innovative culture.

As of January 4, 2022, Roche requires all new employees who work in Canada to be fully vaccinated against COVID-19 on the date they take office. This requirement is a condition of employment at Roche that applies regardless of whether the position is on a Roche campus or remotely.

If you have a valid reason for not being fully immunized, which is limited to certain specific medical reasons or other valid reasons protected by applicable human rights laws, you may request an exemption and / or adaptation measures regarding this vaccination requirement.

Roche is an Equal Opportunity Employer.

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